Seborrhea is a skin disease, often not recognized or underestimated, usually present as a secondary manifestation in dogs and cats with:
- hormonal imbalances;
- flea infestations;
- bacterial or Yeast infections.
It may also be primary, on a hereditary basis, and in this case recognizes a skin keratinization defect.
In its clinical manifestations it can have scales and dry crusts, on an opaque and dull cloak, and in this case, it is referred to as dry seborrhea; or it can have fat scales on a coat matte and oily to the touch, and then we are faced with a fat seborrhea.
In either case, the smell of the skin is unpleasant, because both the seborrheic forms cause itching and are easily complicated with bacterial infections and / or Malassezia.
Starting from these assumptions, ICF formulated Zincoseb® Shampoo.
Indeed, from a practical point of view, primary seborrheas can only be treated with topical therapy, initially with medicated baths 2 times a week and then, having achieved an optimal appearance of the cloak, the baths can be drenched to find a optimal frequency (about once a month), to avoid recurrences, throughout the life of the animal.
This is the case, for example, of granulomatous sebaceous adenitis, dermatitis due to an immunological destruction of the sebaceous glands predominantly found in some predisposed dogs’ breeds, in which a macroscopic level is observed with a keratoseborrous state with desquamation psoriasis or pitirasforms, spotted hair and baldness in long haired dogs, nummolar alopecia areas (rounded “like a coin”), or patchy patches of cloak in short-haired dogs.
On this disease and its topical treatment, Dr. Bensignor, a well-known French dermatologist, has conducted in vivo work, which has led to an improvement in injuries considered significant (over 50% of clinical scores and the owner’s positive assessment) in 7 dogs out of 10 with a good or excellent improvements, with a reduction of more than 75% of injuries, good hair regrowth and owner satisfied or very satisfied.
In particular, the author emphasizes the importance of Zincoseb® Shampoo’s principles: “2% salicylic acid, 0.25% colloidal sulfur, keratolytic agents that reduce desquamation and follicular cylinders; 0.3% of chlorhexidine digluconate, known as antimicrobial agent that allows an antibacterial action useful to decrease secondary infections; 2% lanolin, soothing and emollienting agent that moisturizes the stratum corneum and 2% zinc gluconate is an important micronutrient that has demonstrated a cellular protection activity against external aggression. The topical application of zinc allows significant activity at the skin surface level, but there is also a percutaneous penetration, particularly at the level of the hair follicle, with sebum retention. In vitro, the topical zinc application has been shown to inhibit cell proliferation of keratinocytes and thus has a cholinergic effect (…). Recently, zinc effects have also been demonstrated on re-epithelization. “
In the case of secondary seborrheas, of course, it is essential to treat and resolve the underlying causes, although it is always appropriate, especially in order to accelerate healing times, “targeted” shampoo therapy 1-2 times a week, especially to avoid bacterial complications or yeasts in seborrheic disorders.
Zincoseb® Shampoo is the product of choice because it performs keratolytic functions (removing excess scales on the skin surface) and keratoplasty (normalization of cell replacement in the epidermis layer), but it is also an effective suppressor to antibacterial activity and antifungal.
This action is mainly attributed to the in situ conversion of sulfur to sulfuric acid and pentatonic acid.
Thanks to these peculiarities, he was the protagonist of a live trial conducted by Lisa Graziano and Giovanni Ghibaudo, two well-known veterinarian dermatologists, on 20 dogs with concomitant secondary pathologies and, in addition to clinical and cytological improvement, decreased itching and improved hair quality, the conclusions point out that “… the abolition of these parameters by this anti-boronic shampoo already after the first 2 weeks is of utmost importance, as it allows a quick satisfaction from the owner who is positively at the next clinical checkup. Finally, in view of the results obtained by reducing the microorganisms of this product, we can state that the rational use of shampoos and other antiseptic products could have positive effects on the prevention of antimicrobial resistance by reducing the use of broad spectrum antibiotics in dermatology veterinary and therefore reducing the selective antibiotic pressure.“
In this regard, Zincoseb® Shampoo has demonstrated, in another in vitro study by Luca Guardabassi, Associate Professor of Clinical Microbiology at the University of Copenhagen, an excellent in vitro activity against the target Malassezia target and the major bacterial pathogens associated with it to dog skin infections, which states that “Based on the data produced by this study, Zincoseb® Shampoo can be successfully used in cases of dermatitis in which Malassezia is associated with bacteria, a situation frequently observed in veterinary dermatology. In particular, the most frequent pathogenic bacterium S. Pseudintermedius appears to be highly sensitive to the formulation of Zincoseb® Shampoo. “
Recently, in the European Dermatological Congress of Lausanne ICF also presented Zincoseb® Spray, the ideal complement to Zincoseb® Shampoo.
ICF has the right answer against seborrhea!